Structure activity relationship of phenolic acid inhibitors of α-synuclein fibril formation and toxicity
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چکیده
منابع مشابه
Structure activity relationship of phenolic acid inhibitors of α-synuclein fibril formation and toxicity
The aggregation of α-synuclein (α-syn) is considered the key pathogenic event in many neurological disorders such as Parkinson's disease (PD), dementia with Lewy bodies and multiple system atrophy, giving rise to a whole category of neurodegenerative diseases known as synucleinopathies. Although the molecular basis of α-syn toxicity has not been precisely elucidated, a great deal of effort has ...
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ژورنال
عنوان ژورنال: Frontiers in Aging Neuroscience
سال: 2014
ISSN: 1663-4365
DOI: 10.3389/fnagi.2014.00197